ThinkProgress says Amazing Spider-Man star Andrew Garfield is pushing for a new direction for his character:

Recently, [Garfield] says, he had a philosophical discussion with producer Matt Tolmach about Mary Jane or “MJ” to fans. “I was kind of joking, but kind of not joking about MJ,” he tells EW. “And I was like, ‘What if MJ is a dude?’ Why can’t we discover that Peter is exploring his sexuality? It’s hardly even groundbreaking!…So why can’t he be gay? Why can’t he be into boys?” Garfield even has an actor in mind: “I’ve been obsessed with Michael B. Jordan since The Wire. He’s so charismatic and talented. It’d be even better—we’d have interracial bisexuality!” The star has clearly suggested a sexually flexible Spidey to his director, Marc Webb, as well.

I've got no problem with this. In fact, I think it would play pretty well with Peter Parker's established personality.