Please do fix up the title of Medicine for Melancholy, but thank you so much for mentioning / linking to it and her. That movie is so high on my list of favorites so far this millennium. She's a lovely woman, and Wyatt Cenac, oh my...
Barry Jenkins said that she (from a structured theatrical background) and Wyatt Cenac (from an improvisational background) got along horribly on-set. Although I suppose one could argue that her resulting aloofness is Seberg-esque and helps make Melancholy interesting.