I was quietly pulling for Jonathan Lethem's Chronic City to win the Pulitzer Prize; I think it's an ambitious, artistic novel that should be read by the general-interest audience that the Pulitzer Prize for literature usually attracts.
No such luck. I've never heard of the winner, though the non-fiction choices look solid. Here are the winners in Letters and Drama:
Fiction - Tinkers by Paul Harding (Bellevue Literary Press)
Drama - Next to Normal, music by Tom Kitt, book and lyrics by Brian Yorkey
History - Lords of Finance: The Bankers Who Broke the World by Liaquat Ahamed (The Penguin Press)
Biography - The First Tycoon: The Epic Life of Cornelius Vanderbilt by T.J. Stiles (Alfred A. Knopf)
Poetry - Versed by Rae Armantrout (Wesleyan University Press)
General Nonfiction - The Dead Hand: The Untold Story of the Cold War Arms Race and Its Dangerous Legacy by David E. Hoffman (Doubleday)
You can read a full list of the 2010 Pulitzer winners (including The Seattle Times staff "for its comprehensive coverage, in print and online, of the shooting deaths of four police officers in a coffee house and the 40-hour manhunt for the suspect") over here.